Coalescent-Based DNA Barcoding: Multilocus Analysis and Robustness

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Coalescent-Based DNA Barcoding: Multilocus Analysis and Robustness

DNA barcoding is the assignment of individuals to species using standardized mitochondrial sequences. Nuclear data are sometimes added to the mitochondrial data to increase power. A barcoding method for analysing mitochondrial and nuclear data is developed. It is a Bayesian method based on the coalescent model. Then this method is assessed using simulated and real data. It is found that adding ...

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Supplementary materials for Coalescent - based DNA barcoding : multilocus analysis and robustness

As we need to distinguish the gene of the test individual, samples of genes such as {x, yi} or yi are here considered as ordered. However we wish to relate P (x|yi) to probabilities of unordered samples as efficient methods have been developed to estimate such probabilities. Indeed samples are usually considered as unordered for statistical inference in population genetics since allelic multipl...

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The unprecedented amount of data resulting from next-generation sequencing has opened a new era in phylogenetic estimation. Although large datasets should, in theory, increase phylogenetic resolution, massive, multilocus datasets have uncovered a great deal of phylogenetic incongruence among different genomic regions, due both to stochastic error and to the action of different evolutionary proc...

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The capacity to identify an unknown organism using the DNA sequence from a single gene has many applications. These include the development of biodiversity inventories ( Janzen et al. 2005), forensics (Meiklejohn et al. 2011), biosecurity (Armstrong and Ball 2005), and the identification of cryptic species (Smith et al. 2006). The popularity and widespread use (Teletchea 2010) of the DNA barcod...

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ژورنال

عنوان ژورنال: Journal of Computational Biology

سال: 2012

ISSN: 1066-5277,1557-8666

DOI: 10.1089/cmb.2011.0122